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Biology

What principles govern all living systems?

Life has been running experiments for 3.8 billion years. The principles that survived are worth understanding.

The Principles

Natural Selection

Variation + Selection + Inheritance = Adaptation

ComponentWhat It Means
VariationDifferences exist
SelectionEnvironment filters what survives
InheritanceSurvivors pass on traits
DomainApplication
ProductsShip variations; market selects
IdeasMemes compete; useful ones spread
SkillsPractice creates variation; feedback selects

The question: What are you varying? What's doing the selecting?

Homeostasis

Living systems maintain stable internal conditions despite external change.

MechanismExample
Temperature regulationBody at 37°C whether it's hot or cold
Blood sugarInsulin/glucagon feedback
OrganizationsCulture resists disruption

The question: What are you maintaining stable? At what cost?

Emergence

Simple rules + many agents = complex behavior that no one designed.

LevelEmerges From
ConsciousnessNeurons
MarketsIndividual trades
CultureIndividual actions
Traffic jamsIndividual drivers

The question: What's emerging from the interactions you're enabling?

Compartmentalization

Boundaries concentrate function. Membranes separate inside from outside.

DomainApplication
CellsOrganelles specialize
OrganizationsTeams focus on domains
MindSeparation of concerns

The question: Where do you need boundaries? Where are they too rigid?

Symbiosis

Mutual benefit often beats competition. Cooperation is an evolutionary strategy.

TypeRelationship
MutualismBoth benefit (gut bacteria)
CommensalismOne benefits, other neutral
ParasitismOne benefits, other harmed

The question: What kind of relationship are you in?

Life Cycles

Growth → Maturity → Decay → Renewal

Everything has seasons. Nothing grows forever.

StageCharacteristicsStrategy
GrowthExpansion, investment, buildingInvest aggressively
MaturityStability, optimization, harvestOptimize, extract value
DecayDecline, obsolescenceHarvest or transform
RenewalDeath and rebirthLet go, start fresh

The question: What stage are you in? Are you acting accordingly?

Antifragility

Some systems gain from disorder. Stress makes them stronger.

Response to StressTypeExample
BreaksFragileGlass
UnchangedRobustRock
Gets strongerAntifragileMuscles, immune system

The question: Are you building fragile, robust, or antifragile?

The Meta-Principle

Life creates conditions conducive to life. Surviving systems enable other systems to survive.

This is why:

  • Sustainable beats extractive
  • Ecosystems outperform monocultures
  • Regeneration beats optimization
  • Death enables renewal

Context

  • Evolution — The mechanism
  • Health — Your biological system
  • Play — Life stages and cycles
  • Culture — Emergent social systems